
交付背景
江南大学是国内在发酵工程、化学工程与生物技术领域具有重要影响力的高校。其化学与材料工程领域的研究团队长期致力于新型功能材料与化学合成工艺的探索,对高通量、可重复、数据可追溯的实验平台有着迫切需求。
经过前期充分的工艺评估与方案论证,真泰科技于 2025 年 12 月完成系统交付、整线联调与现场验证,正式将一套化学合成全流程自动化平台移交给江南大学实验室团队。
平台核心能力
多通道液体分配
平台集成真泰科技自研的固定间距移液枪模组(ZT-PM08),支持 1 / 4 / 8 通道灵活切换,适配标准 96 孔板(9mm SBS 板距),单通道移液精度 CV ≤ 1%(100μL)。针对化学合成中多步骤液体添加的需求,系统按配方自动完成试剂加注,逐步弃换吸头以避免交叉污染。
温控反应模块
金属浴恒温反应模块支持室温至 100°C 全范围可编程控温,控温精度 ±0.1°C,适用于需要精确温度曲线的化学合成反应步骤。系统可按实验配方自动切换温度设定值,并实时记录反应过程中的温度变化数据。
六轴机械臂中心枢纽
以六轴机械臂为中枢,完成吸头盒取放、96 孔板转运、溶液瓶开盖与样品干燥等多步骤操作的无缝衔接。末端执行器采用快换接口设计,适配多种操作工具,减少中途人工干预。
全流程数据追溯
每步操作的时间戳、执行参数与传感器数据自动写入系统日志,支持完整的实验过程回溯。审计追踪与权限管理功能确保实验记录可归属、不可篡改,为后续科研发表与成果验证提供可靠的数据依据。
数字孪生接入:平台支持 1:1 数字孪生映射,实验前可在虚拟环境中预演流程,降低试错成本;异常事件可在数字孪生中回放,辅助工艺优化。
关键指标
意义与展望
这是真泰科技在高校科研场景下化学合成自动化领域完成的首套完整交付。与工业制药场景不同,高校科研对实验灵活性与配方可编程性的要求更高,同时对成本与空间约束更为敏感。
本次交付验证了真泰科技"标准底座 + 非标定制"模式在高校科研场景的适用性:以可复用的自动化底座快速适配科研团队的特定工艺需求,缩短从"想法"到"可重复实验"的周期。
未来,真泰科技将持续深化与高校科研机构的合作,探索在材料合成、药物筛选与 AI 驱动实验闭环等方向的进一步应用。
Background
Jiangnan University is a leading Chinese university in fermentation engineering, chemical engineering and biotechnology. Its research teams in chemical and materials engineering have a long-standing focus on novel functional materials and chemical synthesis processes, with an urgent need for high-throughput, reproducible and traceable experimental platforms.
Following thorough process evaluation and solution review, Zhentai completed system delivery, line commissioning and on-site validation in December 2025, formally handing over the full-process chemical synthesis automation platform to the Jiangnan University lab team.
Core platform capabilities
Multi-channel liquid dispensing
The platform integrates Zhentai's in-house fixed-pitch pipette module (ZT-PM08), supporting flexible switching between 1 / 4 / 8 channels for standard 96-well plates (9 mm SBS pitch), with CV ≤ 1% at 100 μL. For multi-step reagent addition in chemical synthesis, the system auto-dispenses per recipe and cycles tips to prevent cross-contamination.
Temperature-controlled reaction module
The metal-bath reaction module supports programmable temperature control from ambient to 100°C with ±0.1°C precision, suitable for synthesis steps requiring precise thermal curves. The system automatically switches setpoints per recipe and logs real-time temperature data throughout the reaction.
Six-axis arm as central hub
A six-axis robotic arm orchestrates tip box pickup, 96-well plate transfer, vial uncapping and sample drying in seamless sequence. Quick-change end effectors accommodate multiple tools, minimizing manual intervention between steps.
End-to-end data traceability
Timestamps, execution parameters and sensor data for every step are automatically logged, supporting complete experimental replay. Audit trails and access control ensure records are attributable and tamper-evident, providing a reliable data basis for publication and result verification.
Digital-twin integration: The platform supports 1:1 digital-twin mapping, enabling process rehearsal in a virtual environment before runs to reduce trial costs; anomalies can be replayed in the digital twin to guide process optimization.
Key metrics
Significance and outlook
This is Zhentai's first complete delivery of a chemical synthesis automation solution in an academic research setting. Unlike industrial pharma, academic research demands greater experimental flexibility and recipe programmability, while being more sensitive to cost and space constraints.
The delivery validates the "standard base + custom builds" model in academic settings: a reusable automation base rapidly adapted to a research team's specific process needs, shortening the cycle from "idea" to "reproducible experiment."
Going forward, Zhentai will deepen collaboration with academic institutions and explore further applications in materials synthesis, drug screening and AI-driven experimental loops.
有类似的化学合成自动化需求?Have a similar chemical synthesis automation need?
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